SLAS

M161 Thomas Dexheimer:Small molecule inhibitors of Bloom helicase identified by a high throughput assay

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Thomas S. Dexheimer1, Giang H. Nguyen2, Andrew Rosenthal1, Wai Kit Chu3, Lena Schultz1, Masaaki Sakurai1, Georgia Mosedale3, Nicola Burgess-Brown4, Curtis C. Harris2, Opher Gileadi4, Ajit Jadhav1, Ian D. Hickson3, David J. Maloney1, and Anton Simeonov1

1 NIH Chemical Genomics Center, NHGRI, NIH, Bethesda, MD 20892-3370; 2 Laboratory of Human Carcinogenesis, CCR, NCI, NIH, Bethesda, MD ; 3 Weatherall Institute of Molecular Medicine, University of Oxford, John Radcliffe Hospital, Oxford, UK; 4 Structural Genomics Consortium, Old Road Campus Research Building, University of Oxford, Roosevelt Drive, Oxford, UK.